Our lab works at the interface between physics, nanotechnology, and biology.
- we build cutting-edge biophysical tools to boost advances in biology and to gain fresh sights of the nature;
- and we observe biology and nature to inspire new physics and to apply physics in novel ways.
We combine quantitative super-resolved fluorescence microscopy (the technique winning the 2014 Nobel Prize in Chemistry »), single-molecule nanometric techniques and statistical physics/modeling to study biological systems at various scales, ranging from individual biological macromolecules (proteins, DNA, RNA) to individual cells/bacteria. We aim to understand quantitatively the fundamental physics that controls the central processes that remain unknown/unclear. More specifically,
- We study the dynamics of plasmids in bacteria to understand their antibiotic resistance and to improve global health.
- We investigate how E. coli bacteria (naturally existing in human guts) respond to different conditions to understand how life adapts to various environments.
- We probe internal motions inside individual biological molecules to understand how nature devises and engineers these molecular machines.
- We engineer biological macromolecules in a different way than nature does and control their functions through physics (i.e. forces).
… read more about the Science in our lab …
The research in our lab has been supported by the following funding agencies.